Penn Pharma, has launched Solusolve, a specialist formulation development service to increase the bioavailability of ‘difficult’ compounds. Solusolve uses several techniques for increasing water-solubility of lipophilic compounds, including salt selection, particle reduction, use of carriers, such as solution formulations and self-emulsifying drug delivery systems, melt extrusion and granulation and functional ‘bioavailability enhancer’ excipients, such as Gelucire and Vitamin E TPGS. Paul Wi...